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The Medicines Company

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

All

Classification:

All

Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Angiox	Bivalirudin	2004-09-20	2028-2039	Acute coronary syndrome , Unstable angina
Ionsys	Fentanyl	2006-05-22	2024-2033	Neoplasms , Pain , Postoperative pain , Psychotic disorders

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

,

,

paroxysmal dyspnea

attention deficit disorder with hyperactivity

sickle cell anemia

,

hematologic neoplasms

,

non-small-cell lung carcinoma

,

,

,

squamous cell carcinoma

,

squamous cell neoplasms

,

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

,

psychotic disorders

renal insufficiency

,

human influenza

healthy volunteers/patients

,

,

bcr-abl positive chronic myelogenous leukemia

,

type 2 diabetes mellitus

,

glandular and epithelial neoplasms

,

,

gata2 deficiency

,

central nervous system neoplasms

,

,

fallopian tube diseases

,

neurologic manifestations

,

,

interdigitating dendritic cell sarcoma

,

myeloproliferative disorders

,

neoplasms by histologic type

,

adenosquamous carcinoma

,

chronic hepatitis c

,

,

venous thromboembolism

,

thromboembolism

,

pharmacokinetics

,

,

behcet syndrome

,

aids-related complex

,

pleural effusion

,

respiratory tract neoplasms

,

bronchogenic carcinoma

,

thoracic neoplasms

,

malignant pleural effusion

,

pleural diseases

,

pleural neoplasms

,

immunosuppression therapy

,

small cell lung carcinoma

,

transitional cell carcinoma

,

ovarian neoplasms

,

non-hodgkin lymphoma

,

triple negative breast neoplasms

,

urologic neoplasms

,

squamous cell carcinoma

,

,

biliary tract neoplasms

,

malignant mesothelioma

,

large b-cell lymphoma diffuse

,

,

uterine cervical neoplasms

,

neoplasms by site

,

castration-resistant prostatic neoplasms

,

b-cell lymphoma

,

endometrial neoplasms

,

,

squamous cell neoplasms

,

,

uveal neoplasms

,

,

hematologic neoplasms

,

t-cell lymphoma peripheral

,

t-cell lymphoma

,

b-cell chronic lymphocytic leukemia

,

,

neuroendocrine tumors

,

gastrointestinal neoplasms

,

adenocarcinoma of lung

,

myeloid leukemia acute

,

cholangiocarcinoma

,

graft vs host disease

,

interstitial lung diseases

,

follicular lymphoma

,

merkel cell carcinoma

,

peritoneal neoplasms

,

spinocerebellar degenerations

,

,

graft rejection

,

psychology rejection

,

clear cell adenocarcinoma

,

,

,

medulloblastoma

,

,

,

rhabdomyosarcoma

,

diffuse intrinsic pontine glioma

,

,

autoimmune diseases

,

multiple sclerosis

,

waldenstrom macroglobulinemia

,

extranodal nk-t-cell lymphoma

,

precursor cell lymphoblastic leukemia-lymphoma

,

burkitt lymphoma

,

female genital neoplasms

,

endometrioid carcinoma

,

,

,

urogenital neoplasms

,

organ transplantation

,

neuroendocrine carcinoma

,

urinary bladder diseases

,

microsatellite instability

,

basal cell carcinoma

,

basal cell neoplasms

,

diffuse scleroderma

,

laryngeal diseases

,

,

heart transplantation

,

,

male breast neoplasms

,

b-cell leukemia

,

tertiary lymphoid structures

,

oropharyngeal neoplasms

,

,

prostatic diseases

,

non-muscle invasive bladder neoplasms

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

diabetic neuropathies

,

nephrotic syndrome

,

focal segmental glomerulosclerosis

,

lipoid nephrosis

,

bronchiolitis obliterans syndrome

,

diabetic nephropathies

,

kidney diseases

,

common variable immunodeficiency

,

large-cell lymphoma anaplastic

,

,

phenylketonurias

,

bile duct neoplasms

,

serous cystadenocarcinoma

,

papillary thyroid cancer

,

,

salivary gland neoplasms

,

genetic therapy

,

smoldering multiple myeloma

,

uterine neoplasms

,

large cell carcinoma

,

endometrial stromal tumors

,

small cell carcinoma

,

penile neoplasms

,

adrenocortical carcinoma

,

digestive system diseases

,

,

,

,

,

invasive hydatidiform mole

,

,

,

,

bronchiolo-alveolar adenocarcinoma

,

drug-related side effects and adverse reactions

,

carcinoid tumor

,

hypersensitivity

,

thyroid neoplasms

,

precancerous conditions

,

bronchopulmonary dysplasia

,

tobacco smoking

,

b-cell lymphoma marginal zone

,

mantle-cell lymphoma

,

meningeal carcinomatosis

,

systemic scleroderma

,

patient preference

,

,

oral leukoplakia

,

churg-strauss syndrome

,

microscopic polyangiitis

,

oligodendroglioma

,

myeloid leukemia

,

,

,

ankylosing spondylitis

,

,

inflammatory breast neoplasms

,

immunoglobulin g4-related disease

,

,

,

progressive multifocal leukoencephalopathy

,

gastrointestinal stromal tumors

,

male urogenital diseases

,

female urogenital diseases

,

female urogenital diseases and pregnancy complications

,

urogenital diseases

,

reactive arthritis

,

hereditary nonpolyposis colorectal neoplasms

,

,

aplastic anemia

,

,

,

non-small-cell lung carcinoma

,

colorectal neoplasms

,

neoplasm metastasis

,

squamous cell carcinoma of head and neck

,

prostatic neoplasms

,

head and neck neoplasms

,

breast neoplasms

,

pancreatic neoplasms

,

liver neoplasms

,

hepatocellular carcinoma

,

urinary bladder neoplasms

,

,

brain neoplasms

,

stomach neoplasms

,

hodgkin disease

,

multiple myeloma

,

,

colonic neoplasms

,

,

rectal neoplasms

,

esophageal neoplasms

,

,

,

,

cutaneous malignant melanoma

,

pancreatic ductal carcinoma

,

fallopian tube neoplasms

,

systemic lupus erythematosus

,

myelodysplastic syndromes

,

plasma cell neoplasms

,

,

ovarian epithelial carcinoma

,

,

,

esophageal squamous cell carcinoma

,

ulcerative colitis

,

juvenile arthritis

,

psoriatic arthritis

,

sjogren's syndrome

,

,

,

lupus nephritis

,

giant cell arteritis

,

respiratory tract diseases

,

granulomatosis with polyangiitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

hyperlipidemias

,

polymyalgia rheumatica

,

vascular diseases

,

,

systemic vasculitis

,

disease progression

,

pathologic complete response

,

,

rheumatoid arthritis

,

renal cell carcinoma

,

,

,

kidney transplantation

,

acquired immunodeficiency syndrome

,

,

kidney neoplasms

,

delayed graft function

,

chronic kidney failure

,

coronary artery disease

,

,

hiv-associated lipodystrophy syndrome

,

epstein-barr virus infections

,

,

transplantation

,

mitochondrial diseases

,

,

,

parkinson disease

,

,

cardiomyopathies

,

dilated cardiomyopathy

,

,

,

alzheimer disease

,

progressive supranuclear palsy

,

,

,

diabetes mellitus

primary myelofibrosis

,

healthy volunteers/patients

,

uterine cervical neoplasms

,

rectal neoplasms

,

cholangiocarcinoma

,

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

colorectal neoplasms

,

stomach neoplasms

,

,

,

ovarian neoplasms

,

triple negative breast neoplasms

,

large b-cell lymphoma diffuse

,

hepatocellular carcinoma

,

liver neoplasms

,

,

,

non-hodgkin lymphoma

,

ulcerative colitis

,

b-cell chronic lymphocytic leukemia

,

small cell lung carcinoma

,

,

neoplasm metastasis

,

b-cell lymphoma

,

,

,

lupus nephritis

,

ductal carcinoma breast

,

macular degeneration

,

,

renal cell carcinoma

,

transitional cell carcinoma

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

urinary bladder neoplasms

,

colonic neoplasms

,

,

head and neck neoplasms

,

,

,

mucinous adenocarcinoma

,

inflammatory breast neoplasms

,

paroxysmal hemoglobinuria

,

pancreatic neoplasms

,

,

,

,

neoplasms by site

,

breast diseases

,

urologic neoplasms

,

prostatic neoplasms

,

,

follicular lymphoma

,

lymphoid leukemia

,

systemic scleroderma

,

diffuse scleroderma

,

retinal vein occlusion

,

,

,

atypical hemolytic uremic syndrome

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

autistic disorder

,

autism spectrum disorder

,

pervasive child development disorders

,

geographic atrophy

,

,

systemic lupus erythematosus

,

nephrotic syndrome

,

ovarian epithelial carcinoma

,

brain neoplasms

,

esophageal squamous cell carcinoma

,

esophageal neoplasms

,

castration-resistant prostatic neoplasms

,

retinal diseases

,

diabetic retinopathy

,

vision disorders

,

,

,

thyroid neoplasms

,

neuroendocrine carcinoma

,

papillary thyroid cancer

,

thyroid diseases

,

disease progression

,

,

endometrioid carcinoma

,

giant cell arteritis

,

type 2 diabetes mellitus

,

diabetes mellitus

,

membranous glomerulonephritis

,

multiple sclerosis

,

chronic progressive multiple sclerosis

,

ankylosing spondylitis

,

spondylarthritis

,

,

myeloid leukemia acute

,

myeloid leukemia

,

alzheimer disease

,

coronary disease

,

acute coronary syndrome

,

coronary artery disease

,

myocardial ischemia

,

,

relapsing-remitting multiple sclerosis

,

guillain-barre syndrome

,

autoimmune diseases of the nervous system

,

bcr-abl positive chronic myelogenous leukemia

,

circulating neoplastic cells

,

disability evaluation

,

cognition disorders

,

cytomegalovirus infections

,

,

,

hemolytic anemia autoimmune

,

,

focal segmental glomerulosclerosis

,

lipoid nephrosis

,

endometrial neoplasms

,

,

graft rejection

,

retinal neovascularization

,

human influenza

,

type 3 von willebrand disease

,

breast neoplasms

,

non-small-cell lung carcinoma

,

,

,

adenocarcinoma of lung

,

,

postmenopausal osteoporosis

healthy volunteers/patients

,

,

ventilator-associated pneumonia

,

respiratory tract infections

,

meningococcal infections

,

pulmonary sarcoidosis

,

meningococcal meningitis

,

migraine disorders

,

,

headache disorders

,

,

,

borrelia infections

,

vector borne diseases

,

knee prosthesis

,

,

tendon injuries

,

,

tissue adhesions

,

hip osteoarthritis

,

,

,

,

high-risk pregnancy

,

intervertebral disc degeneration

,

multiple trauma

,

vascular diseases

,

,

neoplasm metastasis

,

operative surgical procedures

,

urinary retention

,

,

,

physician-nurse relations

,

,

,

traumatic intracranial hemorrhage

,

cardiovascular diseases

,

cerebrovascular disorders

,

central nervous system diseases

,

,

nervous system diseases

,

,

,

,

pulmonary emphysema

,

,

spinal curvatures

,

critical illness

,

pituitary neoplasms

,

pituitary diseases

,

hereditary breast and ovarian cancer syndrome

,

spinal cord neoplasms

,

spinal neoplasms

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

myeloproliferative disorders

,

myelodysplastic-myeloproliferative diseases

,

squamous cell carcinoma

,

hemoglobinometry

,

,

traumatic brain injuries

,

,

von willebrand diseases

,

,

hyperpigmentation

,

,

,

,

hematologic neoplasms

,

,

pulmonary hypertension

,

hereditary hemorrhagic telangiectasia

,

,

hemorrhagic shock

,

thrombocytopenia

,

transfusion reaction

,

coronary artery bypass

,

,

chronic renal insufficiency

,

,

urinary bladder neoplasms

,

accidental injuries

,

,

traumatic brain hemorrhage

,

lung transplantation

,

spinal dysraphism

,

,

intraoperative complications

,

aortic dissection

,

brain neoplasms

,

,

,

head and neck neoplasms

,

acute kidney injury

,

,

transcatheter aortic valve replacement

,

hereditary angioedemas

,

female genital neoplasms

,

,

,

obstetric labor

,

,

hematopoietic stem cell transplantation

,

,

subarachnoid hemorrhage

,

carotid artery diseases

,

spinal injuries

,

abdominal aortic aneurysm

,

,

aortic aneurysm

,

pathologic processes

,

,

,

pancreatic neoplasms

,

,

femoracetabular impingement

,

,

surgical wound infection

,

,

,

,

agranulocytosis

,

feeding behavior

,

replacement arthroplasty shoulder

,

,

,

,

,

surgical blood loss

,

postpartum hemorrhage

,

postoperative hemorrhage

,

,

knee osteoarthritis

,

,

,

,

,

obstetric labor complications

,

replacement arthroplasty knee

,

postoperative pain

,

,

wounds and injuries

,

,

placenta previa

,

hemostatic disorders

,

blood coagulation disorders

,

gastrointestinal hemorrhage

,

uterine hemorrhage

,

replacement arthroplasty hip

,

blood transfusion

,

cerebral hemorrhage

,

,

drug-related side effects and adverse reactions

,

,

cardiac surgical procedures

,

,

subdural hematoma

,

subdural hematoma chronic

,

,

rotator cuff injuries

,

,

,

,

femoral fractures

,

,

,

venous thrombosis

,

cesarean section

,

coronary artery disease

,

,

,

postoperative complications

,

breast neoplasms

,

cardiopulmonary bypass

,

,

,

,

,

,

thromboembolism

,

,

,

congenital heart defects

,

,

anterior cruciate ligament injuries

,

,

,

liver cirrhosis

,

,

nephrolithiasis

,

,

ovarian neoplasms

,

uterine myomectomy

,

anterior cruciate ligament reconstruction

,

,

femoral neck fractures

,

craniosynostoses

,

bariatric surgery

,

,

musculoskeletal diseases

,

congenital abnormalities

,

healthy volunteers/patients

,

,

venous thromboembolism

,

paranasal sinus diseases

,

shoulder impingement syndrome

,

prostatic neoplasms

,

,

placenta accreta

,

spinal stenosis

,

,

intracranial hemorrhages

,

stomach neoplasms

,

,

prostatic hyperplasia

,

hypersensitivity

,

,

nasal obstruction

,

,

pathologic dilatation

,

urologic diseases

,

patient satisfaction

,

,

,

,

orthognathic surgery

,

tooth extraction

,

pregnancy complications

,

pelvic organ prolapse

,

hemorrhagic stroke

,

,

,

liver neoplasms

,

colonic neoplasms

,

ovarian epithelial carcinoma

,

radius fractures

,

wrist fractures

,

,

humeral fractures

,

percutaneous nephrolithotomy

,

,

opioid-related disorders

,

,

deficiency diseases

,

chronic urticaria

,

,

,

injection site reaction

,

,

cross infection

,

wound infection

,

,

,

,

colorectal neoplasms

,

uterine inertia

,

staghorn calculi

,

myocardial infarction

,

pulmonary embolism

,

,

hemiarthroplasty

,

arteriovenous fistula

,

,

pathologic constriction

,

gynecologic surgical procedures

,

rheumatic diseases

,

,

,

,

,

pancreaticoduodenectomy

,

,

biliary tract surgical procedures

,

,

,

dupuytren contracture

,

,

,

,

esophageal neoplasms

,

duodenal neoplasms

,

heart valve diseases

,

prospective studies

,

randomized controlled trials as topic

,

eyelid diseases

,

,

shoulder fractures

,

shoulder injuries

,

contraceptive devices

,

,

,

autoimmune diseases

,

intravenous administration

,

,

,

urethral stricture

,

urethral diseases

,

,

,

hyperaldosteronism

,

pulmonary arterial hypertension

,

urinary tract infections

,

,

sleep initiation and maintenance disorders

,

cardiac arrhythmias

,

,

,

liver transplantation

,

spinal cord diseases

,

blood platelet disorders

,

,

pigmentation disorders

,

heterotopic ossification

,

coronavirus infections

,

,

mucocutaneous lymph node syndrome

,

hyperphosphatemia

,

bronchopulmonary dysplasia

,

adrenal insufficiency

,

,

,

coagulation protein disorders

,

attention deficit disorder with hyperactivity

,

,

rheumatoid arthritis

,

replacement arthroplasty

,

kidney diseases

,

respiratory tract infections

,

,

,

migraine disorders

,

,

,

communicable diseases

,

bacterial infections

,

intraabdominal infections

,

healthcare-associated pneumonia

,

methicillin-resistant staphylococcus aureus

,

,

staphylococcal infections

,

,

,

general anesthesia

,

,

,

gram-negative bacterial infections

,

,

bacterial meningitis

,

,

central nervous system infections

,

neuromuscular blockade

,

,

,

cytomegalovirus retinitis

,

,

adenoviridae infections

,

port-wine stain

,

,

,

capillary hemangioma

,

,

bipolar disorder

,

autistic disorder

,

,

treatment-resistant schizophrenia

,

potassium deficiency

,

,

iron-deficiency anemia

,

iron deficiencies

,

diabetes insipidus

,

cytoreduction surgical procedures

,

primary graft dysfunction

,

intervertebral disc displacement

,

,

congenital hip dislocation

,

femur head necrosis

,

,

acute lung injury

,

retinal diseases

,

factor xi deficiency

,

closed fractures

,

orthopedic procedures

,

erythrocyte transfusion

,

neurosurgical procedures

,

lacrimal duct obstruction

,

off-pump coronary artery bypass

,

spinal cord compression

,

hematologic diseases

,

recreational drug use

,

,

peptic ulcer hemorrhage

,

osteogenesis imperfecta

,

skin pigmentation

,

obstetric delivery

,

,

,

obstetrical anesthesia

,

perinatal death

,

abruptio placentae

,

prolonged pregnancy

,

,

transurethral resection of prostate

,

,

vaginal hysterectomy

,

,

cardiovascular surgical procedures

,

lens subluxation

,

joint dislocations

,

fracture dislocation

,

elbow fractures

,

dermatofibrosarcoma

,

spontaneous fractures

,

thoracic surgical procedures

,

autologous blood transfusion

,

,

,

retinal detachment

,

diabetic retinopathy

,

renal insufficiency

,

,

spinal anesthesia

,

,

ear acupuncture

,

acupuncture analgesia

,

acupuncture therapy

,

,

end stage liver disease

,

allergic rhinitis

,

,

,

,

inherited blood coagulation disorders

,

tibial fractures

P2y purinoceptor 12

blood flow velocity

,

coronary circulation

,

pathologic processes

,

chronic obstructive pulmonary disease

,

obstructive lung diseases

,

,

ischemic stroke

,

,

,

kidney diseases

,

sickle cell anemia

,

,

respiratory tract infections

,

respiratory tract diseases

,

,

human influenza

,

community-acquired pneumonia

,

pancreatic ductal carcinoma

,

pancreatic neoplasms

,

,

graft rejection

,

cerebral infarction

,

coronary artery disease

,

acute coronary syndrome

,

myocardial infarction

,

,

coronary disease

,

myocardial ischemia

,

,

percutaneous coronary intervention

,

st elevation myocardial infarction

,

,

platelet aggregation

,

atrial fibrillation

,

cardiovascular diseases

,

,

unstable angina

,

dual anti-platelet therapy

,

,

inferior wall myocardial infarction

,

peripheral arterial disease

,

non-st elevated myocardial infarction

,

,

intracranial aneurysm

,

atherosclerosis

,

drug-eluting stents

,

,

coronary stenosis

,

healthy volunteers/patients

,

chronic renal insufficiency

,

,

,

endovascular procedures

,

peripheral vascular diseases

,

,

drug interactions

,

arteriosclerosis

,

,

,

cardiogenic shock

,

vascular diseases

,

ventricular remodeling

,

,

,

aortic valve stenosis

,

,

angina pectoris

,

platelet activation

,

platelet function tests

,

,

induced hypothermia

,

stomatognathic diseases

,

,

out-of-hospital cardiac arrest

,

migraine disorders

,

,

type 2 diabetes mellitus

,

,

thrombocytopenia

,

renal insufficiency

,

hematologic diseases

,

,

blood coagulation disorders

,

hemorrhagic stroke

,

hemostatic disorders

,

coagulation protein disorders

,

heart valve prosthesis

,

cerebral hemorrhage

,

subarachnoid hemorrhage

,

,

nervous system diseases

,

coronary thrombosis

,

drug resistance

,

,

disseminated intravascular coagulation

,

heart disease risk factors

,

,

systemic inflammatory response syndrome

,

,

postoperative hemorrhage

,

surgical blood loss

,

,

,

,

endomyocardial fibrosis

,

cerebrovascular disorders

,

stomach neoplasms

,

blood transfusion

,

extracorporeal membrane oxygenation

,

drug-related side effects and adverse reactions

,

pharmacogenomic testing

,

,

cardiomyopathies

,

,

intracranial arteriosclerosis

,

diabetes mellitus

,

arterial occlusive diseases

,

surgical amputation

,

essential thrombocythemia

,

nontuberculous mycobacterium infections

Fluoroquinolone

,

type 2 diabetes mellitus

,

long qt syndrome

,

,

alzheimer disease

,

,

,

,

,

,

photosensitivity disorders

,

chronic renal insufficiency

,

kidney diseases

,

migraine disorders

,

pulmonary arterial hypertension

,

,

coronary artery disease

,

cardiovascular abnormalities

,

erectile dysfunction

,

major depressive disorder

,

electrocardiography

,

,

,

,

rheumatoid arthritis

,

,

,

therapeutic equivalency

,

,

psychotic disorders

,

,

thrombocytopenic purpura idiopathic

,

,

renal cell carcinoma

,

polycythemia vera

,

duchenne muscular dystrophy

,

autoimmune diseases

,

orthostatic hypotension

,

acute coronary syndrome

,

lecithin cholesterol acyltransferase deficiency

,

,

lice infestations

,

restless legs syndrome

,

marijuana abuse

,

falciparum malaria

,

allergic rhinitis

,

,

retinal diseases

,

,

,

alcoholic liver cirrhosis

,

alcoholic hepatitis

,

hepatolenticular degeneration

,

,

acinetobacter infections

,

systemic lupus erythematosus

,

,

renal insufficiency

,

,

premature obstetric labor

,

premature birth

,

,

,

respiration disorders

,

,

,

,

,

human experimentation

,

myocardial ischemia

,

phase i metabolic detoxication

,

periapical periodontitis

,

,

phototoxic dermatitis

,

,

,

,

,

short bowel syndrome

,

non-alcoholic fatty liver disease

,

alcoholic fatty liver

,

smoking cessation

,

multiple endocrine neoplasia type 1

,

postpartum hemorrhage

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

respiratory syncytial virus infections

,

bacterial vaginosis

,

retinal vein occlusion

,

,

choroidal neovascularization

,

pathologic neovascularization

,

sickle cell anemia

,

,

,

pharmacokinetics

,

,

escherichia coli infections

,

,

infectious arthritis

,

,

,

,

otorhinolaryngologic diseases

,

parkinson disease

,

methicillin-resistant staphylococcus aureus

,

,

pharmacological phenomena

,

pulmonary sarcoidosis

,

,

refractive errors

,

,

pancreatic ductal carcinoma

,

systemic inflammatory response syndrome

,

,

,

,

amyotrophic lateral sclerosis

,

anastomotic leak

,

cutaneous leishmaniasis

,

mycobacterium avium-intracellulare infection

,

staphylococcal skin infections

,

,

head and neck neoplasms

,

squamous cell carcinoma

,

squamous cell neoplasms

,

neoplasm metastasis

,

,

anorexia nervosa

,

,

,

graft vs host disease

,

muscle spasticity

,

interstitial lung diseases

,

myeloid leukemia

,

lymphoid leukemia

,

hepatopulmonary syndrome

,

corneal injuries

,

,

rectal neoplasms

,

,

,

castration-resistant prostatic neoplasms

,

periapical diseases

,

colorectal neoplasms

,

,

,

,

,

acquired immunodeficiency syndrome

,

,

,

,

,

community-acquired infections

,

extensively drug-resistant tuberculosis

,

multiple myeloma

,

respiratory tract diseases

,

latent tuberculosis

,

myelodysplastic syndromes

,

infectious skin diseases

,

bacterial skin diseases

,

,

,

mycobacterium infections

,

prosthesis-related infections

,

wounds and injuries

,

large b-cell lymphoma diffuse

,

aids-related opportunistic infections

,

,

b-cell chronic lymphocytic leukemia

,

hodgkin disease

,

plasma cell neoplasms

,

,

,

,

,

congenital abnormalities

,

,

healthcare-associated pneumonia

,

urologic diseases

,

bronchial diseases

,

myeloproliferative disorders

,

sezary syndrome

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

mantle-cell lymphoma

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

burkitt lymphoma

,

large-cell lymphoma immunoblastic

,

,

clostridium infections

,

meningeal tuberculosis

,

human influenza

,

nontuberculous mycobacterium infections

,

enterobacteriaceae infections

,

neurogenic urinary bladder

,

biphenotypic leukemia acute

,

,

,

,

wound infection

,

abdominal abscess

,

pelvic infection

,

ovarian neoplasms

,

primary myelofibrosis

,

myelomonocytic leukemia chronic

,

myelodysplastic-myeloproliferative diseases

,

myeloid leukemia chronic-phase

,

myeloid leukemia accelerated phase

,

hairy cell leukemia

,

testicular neoplasms

,

,

paranasal sinus diseases

,

,

hematopoietic stem cell transplantation

,

large-cell lymphoma anaplastic

,

immunoblastic lymphadenopathy

,

intraocular lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

central nervous system neoplasms

,

,

,

phenylketonurias

,

mycobacterium tuberculosis

,

,

,

,

musculoskeletal pain

,

systolic heart failure

,

sick sinus syndrome

,

,

,

gram-positive bacterial infections

,

triple negative breast neoplasms

,

,

,

leukemia myeloid chronic atypical bcr-abl negative

,

gestational trophoblastic disease

,

ovarian epithelial carcinoma

,

neutrophilic leukemia chronic

,

trophoblastic neoplasms

,

nervous system diseases

,

hereditary congenital and neonatal diseases and abnormalities

,

neural tube defects

,

nervous system malformations

,

spinal dysraphism

,

ocular hypertension

,

open-angle glaucoma

,

,

,

sphenoid sinusitis

,

,

prolymphocytic leukemia

,

large granular lymphocytic leukemia

,

,

small cell lung carcinoma

,

phacoemulsification

,

acute cholecystitis

,

,

esophageal and gastric varices

,

intestinal neoplasms

,

nervous system neoplasms

,

salivary gland diseases

,

neurologic manifestations

,

,

acquired joint deformities

,

,

hematologic diseases

,

acanthamoeba keratitis

,

agammaglobulinemia

,

hidradenitis suppurativa

,

,

lymph node tuberculosis

,

prostatic diseases

,

healthy volunteers/patients

,

,

urinary tract infections

,

communicable diseases

,

,

,

pulmonary tuberculosis

,

chronic obstructive pulmonary disease

,

bacterial infections

,

multidrug-resistant tuberculosis

,

helicobacter infections

,

community-acquired pneumonia

,

,

,

,

,

,

respiratory tract infections

,

chronic bronchitis

,

,

bacterial conjunctivitis

,

,

,

liver cirrhosis

,

,

,

bacterial pneumonia

,

,

cystic fibrosis

,

endophthalmitis

,

,

febrile neutropenia

,

myeloid leukemia acute

,

,

,

,

diabetes mellitus

,

,

,

prostatic neoplasms

,

breast neoplasms

,

,

cataract extraction

,

,

,

disease susceptibility

,

precursor cell lymphoblastic leukemia-lymphoma

,

disease progression

,

non-hodgkin lymphoma

,

pseudomonas infections

,

,

,

,

,

,

,

intraabdominal infections

,

,

respiratory aspiration

,

,

,

urinary bladder neoplasms

,

,

corneal diseases

,

,

,

cardiovascular diseases

,

surgical wound infection

,

,

,

,

maxillary sinusitis

,

critical illness

,

nephrolithiasis

,

,

,

insulin resistance

,

,

drug-related side effects and adverse reactions

,

prostatic hyperplasia

,

microbial drug resistance

,

retinal detachment

,

obstructive lung diseases

,

overactive urinary bladder

,

,

ventilator-associated pneumonia

,

,

inflammatory bowel diseases

,

dental pulp necrosis

,

,

postoperative pain

,

,

cardiac arrhythmias

,

cross infection

,

,

pelvic inflammatory disease

,

,

,

antibiotic prophylaxis

,

,

hematologic neoplasms

,

bacillary dysentery

,

,

mycoplasma pneumonia

,

pyogenic liver abscess

,

osteoarticular tuberculosis

,

,

ulcerative colitis

,

otitis media with effusion

,

pancreatic neoplasms

,

macular degeneration

,

pseudomonas aeruginosa

,

,

hypersensitivity

,

aspiration pneumonia

,

chronic periodontitis

,

corneal transplantation

,

bacterial eye infections

,

aggressive periodontitis

,

soft tissue infections

,

meningococcal meningitis

,

pancreatic cyst

,

gastroenteritis

,

postoperative complications

,

chlamydia infections

,

adaptive immunity

,

klebsiella infections

,

,

pneumococcal pneumonia

,

periapical abscess

,

patient preference

,

suppurative otitis media

,

,

,

intravenous substance abuse

,

contraception behavior

,

heart disease risk factors

,

glucose intolerance

,

,

,

intravitreal injections

,

patient compliance

,

metabolic syndrome

,

,

intravesical administration

,

non-muscle invasive bladder neoplasms

,

mycoplasma pneumoniae

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

kidney transplantation

,

polyomavirus infections

,

,

,

,

,

penetrating eye injuries

,

,

ophthalmologic surgical procedures

,

hepatorenal syndrome

,

,

hereditary angioedemas

,

ureteral calculi

,

,

herpesviridae infections

,

,

,

pulmonary infarction

,

haemophilus infections

,

,

urinary diversion

,

,

colonic diverticulitis

,

,

staphylococcal infections

,

,

ischemic stroke

,

bacterial drug resistance

,

staphylococcus aureus

,

,

pathologic dilatation

,

drug monitoring

,

deglutition disorders

,

clostridioides difficile

,

,

aortic dissection

,

,

mycoplasma infections

,

pleuropneumonia

,

,

inappropriate prescribing

,

chemical and drug induced liver injury

,

,

venous thrombosis

,

drug resistance

,

,

,

,

,

,

,

hyperaldosteronism

,

,

sleep initiation and maintenance disorders

,

,

,

,

general anesthesia

,

,

,

,

gram-negative bacterial infections

,

,

bacterial meningitis

,

central nervous system infections

,

neuromuscular blockade

,

,

,

cytomegalovirus retinitis

,

,

adenoviridae infections

,

port-wine stain

,

,

,

capillary hemangioma

,

bipolar disorder

,

autistic disorder

,

,

,

treatment-resistant schizophrenia

,

potassium deficiency

,

asymptomatic infections

,

,

,

extracorporeal circulation

,

,

,

precancerous conditions

,

,

,

stenotrophomonas maltophilia

,

percutaneous nephrolithotomy

,

,

dissociative disorders

,

,

reactive arthritis

,

chronic kidney failure

,

musculoskeletal diseases

,

catheter-related infections

,

portal hypertension

,

myocardial revascularization

,

emergency treatment

,

,

,

multiple drug resistance

,

physical exertion

,

laboratory infection

,

,

uterine hemorrhage

,

spontaneous abortion

,

blood transfusion

,

lymphatic diseases

,

traumatic brain injuries

,

pleural empyema

,

root resorption

,

persistent infection

,

torsades de pointes

,

emerging communicable diseases

,

,

emergence delirium

therapeutic equivalency

,

,

,

depressive disorder

,

acquired immunodeficiency syndrome

,

,

major depressive disorder

,

hemolytic anemia

,

head and neck neoplasms

,

,

blood platelet disorders

,

coronavirus infections

,

respiratory insufficiency

,

viral pneumonia

,

cognition disorders

,

,

obstructive lung diseases

,

critical illness

,

polycythemia vera

,

,

pathologic processes

,

diabetic retinopathy

,

breast neoplasms

,

neoplasm metastasis

,

pulmonary hypertension

,

salivary gland neoplasms

,

squamous cell carcinoma of head and neck

,

,

disease susceptibility

,

,

,

patent foramen ovale

,

cognitive dysfunction

,

chronic obstructive pulmonary disease

,

thromboembolism

,

congenital heart defects

,

,

,

cerebral hemorrhage

,

,

heart valve diseases

,

coronary artery bypass

,

vertebral artery dissection

,

respiratory tract infections

,

respiratory tract diseases

,

human influenza

,

community-acquired pneumonia

,

heart transplantation

,

,

intracranial hemorrhages

,

ventricular outflow obstruction

,

pancreatic ductal carcinoma

,

pancreatic neoplasms

,

,

middle cerebral artery infarction

,

,

internal carotid artery dissection

,

,

chronic kidney failure

,

,

renal insufficiency

,

vascular dementia

,

follicular lymphoma

,

disease progression

,

macular degeneration

,

,

coronary artery disease

,

acute coronary syndrome

,

myocardial infarction

,

ischemic stroke

,

coronary disease

,

myocardial ischemia

,

,

healthy volunteers/patients

,

,

percutaneous coronary intervention

,

,

cardiovascular diseases

,

,

peripheral arterial disease

,

atrial fibrillation

,

,

st elevation myocardial infarction

,

,

atherosclerosis

,

,

diabetes mellitus

,

type 2 diabetes mellitus

,

,

cerebral infarction

,

transient ischemic attack

,

platelet aggregation

,

unstable angina

,

carotid stenosis

,

vascular diseases

,

chronic renal insufficiency

,

intracranial arteriosclerosis

,

peripheral vascular diseases

,

aortic valve stenosis

,

angina pectoris

,

inferior wall myocardial infarction

,

,

dual anti-platelet therapy

,

migraine disorders

,

arterial occlusive diseases

,

intracranial aneurysm

,

kidney diseases

,

non-st elevated myocardial infarction

,

pathologic constriction

,

chronic limb-threatening ischemia

,

,

drug-eluting stents

,

aortic valve disease

,

,

arteriosclerosis

,

coronary stenosis

,

,

coronary aneurysm

,

,

intermittent claudication

,

endovascular procedures

,

transcatheter aortic valve replacement

,

pharmacological phenomena

,

drug interactions

,

embolism and thrombosis

,

,

intracranial embolism

,

balloon angioplasty coronary

,

secondary prevention

,

ventricular remodeling

,

,

coronary thrombosis

,

,

metabolic syndrome

,

,

,

venous thromboembolism

,

,

,

endomyocardial fibrosis

,

no-reflow phenomenon

,

gastrointestinal hemorrhage

,

pharmacokinetics

,

staphylococcal infections

,

cerebral small vessel diseases

,

chinese traditional medicine

,

glucosephosphate dehydrogenase deficiency

,

,

gastrointestinal diseases

,

retinal artery occlusion

,

myocardial stunning

,

retinal diseases

,

,

post-cardiac arrest syndrome

,

,

drug-related side effects and adverse reactions

,

bites and stings

,

coronary restenosis

,

atrial heart septal defects

,

,

female infertility

,

stomatognathic diseases

,

systolic heart failure

,

,

ankle brachial index

,

,

atherosclerotic plaque

,

diabetic nephropathies

,

,

,

platelet activation

,

mucocutaneous lymph node syndrome

,

,

venous thrombosis

,

psoriatic arthritis

,

,

surgical blood loss

,

,

carotid artery diseases

,

,

asymptomatic diseases

,

cerebrovascular disorders

,

coronary occlusion

,

cerebral amyloid angiopathy

,

familial cerebral amyloid angiopathy

,

,

,

,

drug resistance

,

,

,

femoral neck fractures

,

carotid artery injuries

,

migraine with aura

,

heart disease risk factors

,

,

acute kidney injury

,

,

acute liver failure

,

,

,

hypercholesterolemia

,

magnetic resonance imaging

,

,

postoperative hemorrhage

,

,

,

antiphospholipid syndrome

,

anterior wall myocardial infarction

,

,

vertebrobasilar insufficiency

,

bariatric surgery

,

peptic ulcer hemorrhage

,

thrombocytopenia

,

aortic diseases

,

takayasu arteritis

,

systemic vasculitis

,

,

cardiac arrhythmias

,

surgical amputation

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