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Company ReportsThe Medicines Company

The Medicines Company

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

All

Classification:

All

Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Angiox	Bivalirudin	2004-09-20	2028-2039	Acute coronary syndrome , Unstable angina
Ionsys	Fentanyl	2006-05-22	2024-2033	Neoplasms , Pain , Postoperative pain , Psychotic disorders

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

,

,

paroxysmal dyspnea

venous thrombosis

,

healthy volunteers/patients

,

carotid artery diseases

,

cardiogenic shock

,

congenital heart defects

,

cardiomyopathies

,

coronary artery bypass

,

,

cardiovascular diseases

,

,

,

subarachnoid hemorrhage

,

,

intracranial aneurysm

,

endovascular procedures

,

aortic valve stenosis

,

transcatheter aortic valve replacement

,

hematologic diseases

,

cardiac surgical procedures

,

,

,

myocardial infarction

,

,

coronary artery disease

,

st elevation myocardial infarction

,

acute coronary syndrome

,

coronary disease

,

myocardial ischemia

,

percutaneous coronary intervention

,

,

inferior wall myocardial infarction

,

,

,

,

non-st elevated myocardial infarction

,

unstable angina

,

thrombocytopenia

,

,

,

balloon angioplasty coronary

,

respiratory distress syndrome

,

blood coagulation disorders

,

hemostatic disorders

,

angina pectoris

,

,

atherosclerosis

,

carotid stenosis

,

microvascular angina

,

respiratory insufficiency

mucopolysaccharidoses

,

sudden infant death

,

mucopolysaccharidosis ii

,

lysosomal storage diseases

gastrointestinal stromal tumors

,

,

iron-deficiency anemia

,

iron deficiencies

,

,

,

,

small cell lung carcinoma

,

healthy volunteers/patients

,

,

,

,

primary myelofibrosis

,

myeloid leukemia acute

,

myeloid leukemia

,

prostatic neoplasms

,

,

hepatocellular carcinoma

,

plexiform neurofibroma

,

neurofibromatoses

,

,

,

,

chronic obstructive pulmonary disease

,

,

,

triple negative breast neoplasms

,

,

,

essential thrombocythemia

,

polycythemia vera

,

,

,

lupus nephritis

,

inflammatory breast neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

wiskott-aldrich syndrome

,

bcr-abl positive chronic myelogenous leukemia

,

,

hematopoietic stem cell transplantation

,

bronchiolitis obliterans syndrome

,

,

hyperlipoproteinemia type ii

,

graft vs host disease

,

organ transplantation

,

homozygous familial hypercholesterolemia

,

cryopyrin-associated periodic syndromes

,

,

psychology rejection

,

myelodysplastic syndromes

,

,

liver transplantation

,

thrombocytopenic purpura idiopathic

,

thrombocytopenic purpura

,

,

parkinson disease

,

,

,

,

juvenile arthritis

,

,

,

hepatitis b virus

,

,

,

pituitary acth hypersecretion

,

,

acute coronary syndrome

,

,

myocardial infarction

,

coronary stenosis

,

atherosclerotic plaque

,

,

,

hypersensitivity

,

pulmonary eosinophilia

,

pancreatic neoplasms

,

,

,

kidney transplantation

,

,

hypercholesterolemia

,

atherosclerosis

,

breast neoplasms

,

,

hyperlipidemias

,

cardiovascular diseases

,

chronic kidney failure

,

kidney diseases

,

thrombocytopenia

,

,

,

coronary artery disease

,

,

,

chronic renal insufficiency

,

,

renal replacement therapy

,

renal insufficiency

,

drug-related side effects and adverse reactions

,

heart transplantation

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

,

cystic fibrosis

,

pseudomonas infections

,

type 2 diabetes mellitus

,

,

multiple myeloma

,

plasma cell neoplasms

,

transplantation

,

cytomegalovirus infections

,

communicable diseases

,

neoplasm metastasis

,

metabolic syndrome

,

preconception care

,

drug interactions

,

percutaneous coronary intervention

,

,

healthy volunteers/patients

,

,

central nervous system neoplasms

,

nephrotic syndrome

,

laryngeal diseases

,

chronic hepatitis

,

,

esophageal neoplasms

,

postmenopausal osteoporosis

,

,

irritable bowel syndrome

,

pathologic dilatation

,

germ cell and embryonal neoplasms

,

medulloblastoma

,

,

,

choroid plexus neoplasms

,

oligodendroglioma

,

primitive neuroectodermal tumors

,

,

,

neuroepithelial neoplasms

,

hypertrophic pyloric stenosis

,

ganglioneuroblastoma

,

phenylketonurias

,

neuroendocrine tumors

,

b-cell lymphoma marginal zone

,

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

rectal diseases

,

gastrointestinal diseases

,

intestinal neoplasms

,

digestive system diseases

,

colonic diseases

,

intestinal diseases

,

autism spectrum disorder

,

drug hypersensitivity

,

renal cell carcinoma

,

,

,

squamous cell carcinoma of head and neck

,

head and neck neoplasms

,

b-cell lymphoma

,

squamous cell carcinoma

,

large b-cell lymphoma diffuse

,

pancreatic ductal carcinoma

,

,

,

uveal neoplasms

,

,

mantle-cell lymphoma

,

multiple myeloma

,

myocardial infarction

,

kidney neoplasms

,

hereditary sensory and autonomic neuropathies

,

myelodysplastic syndromes

,

endometrial neoplasms

,

bronchiolitis obliterans syndrome

,

coronary artery disease

,

hypersensitivity

,

philadelphia chromosome

,

lymphoid leukemia

,

,

squamous cell neoplasms

,

waldenstrom macroglobulinemia

,

myeloid leukemia acute

,

castration-resistant prostatic neoplasms

,

hypertrophic cardiomyopathy

,

acute coronary syndrome

,

myocardial ischemia

,

unstable angina

,

margins of excision

,

gouty arthritis

,

gastrointestinal stromal tumors

,

,

,

retinitis pigmentosa

,

,

,

,

,

portal hypertension

,

atopic dermatitis

,

,

,

,

peritoneal neoplasms

,

intestinal obstruction

,

invasive hydatidiform mole

,

central serous chorioretinopathy

,

,

epstein-barr virus infections

,

oropharyngeal neoplasms

,

hodgkin disease

,

type 1 diabetes mellitus

,

,

neurofibrosarcoma

,

ovarian neoplasms

,

fallopian tube neoplasms

,

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

netherton syndrome

,

,

eosinophilic esophagitis

,

,

systemic mastocytosis

,

mast-cell leukemia

,

,

,

female infertility

,

sickle cell anemia

,

streptococcus agalactiae

,

angioid streaks

,

pseudoxanthoma elasticum

,

granulomatosis with polyangiitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

microscopic polyangiitis

,

diffuse scleroderma

,

t-cell lymphoma

,

malignant mesothelioma

,

clear cell adenocarcinoma

,

,

adenomyoepithelioma

,

colorectal neoplasms

,

non-small-cell lung carcinoma

,

,

bcr-abl positive chronic myelogenous leukemia

,

,

,

prostatic neoplasms

,

,

myeloid leukemia

,

triple negative breast neoplasms

,

,

follicular lymphoma

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

,

cardiovascular diseases

,

hypercholesterolemia

,

graft vs host disease

,

,

psoriatic arthritis

,

,

rheumatoid arthritis

,

non-hodgkin lymphoma

,

meningococcal meningitis

,

meningococcal infections

,

rectal neoplasms

,

osteitis deformans

,

,

degenerative myopia

,

stomach neoplasms

,

,

neoplasms by site

,

inferior wall myocardial infarction

,

,

psychology rejection

,

organ transplantation

,

graft rejection

,

adenocarcinoma of lung

,

,

aplastic anemia

,

,

carcinoid tumor

,

,

chronic hepatitis c

,

lupus nephritis

,

,

colonic neoplasms

,

retinopathy of prematurity

,

polycythemia vera

,

male breast neoplasms

,

,

,

,

hematologic neoplasms

,

neoplasms by histologic type

,

left ventricular dysfunction

,

st elevation myocardial infarction

,

non-st elevated myocardial infarction

,

,

,

,

infectious skin diseases

,

soft tissue infections

,

,

malignant carcinoid syndrome

,

serotonin syndrome

,

erectile dysfunction

,

peanut hypersensitivity

,

allergic rhinitis seasonal

,

,

,

haemophilus infections

,

,

cerebrotendinous xanthomatosis

,

,

muscular diseases

,

muscular atrophy

,

spinal muscular atrophy

,

x-linked bulbo-spinal atrophy

,

neovascular glaucoma

,

,

thrombocytopenic purpura idiopathic

,

thrombocytopenia

,

chronic obstructive pulmonary disease

,

,

alpha 1-antitrypsin deficiency

,

lymphoproliferative disorders

,

primary myelofibrosis

,

,

breast neoplasms

,

,

macular degeneration

,

,

,

,

kidney transplantation

,

vision disorders

,

choroidal neovascularization

,

type 2 diabetes mellitus

,

neoplasm metastasis

,

retinal vein occlusion

,

chronic urticaria

,

diabetes mellitus

,

liver transplantation

,

essential hypertension

,

multiple sclerosis

,

diabetic retinopathy

,

brain neoplasms

,

relapsing-remitting multiple sclerosis

,

kidney diseases

,

metabolic syndrome

,

renal insufficiency

,

,

pancreatic neoplasms

,

,

chronic kidney failure

,

,

retinal diseases

,

systolic heart failure

,

insulin resistance

,

,

geographic atrophy

,

parkinson disease

,

diastolic heart failure

,

chronic renal insufficiency

,

,

diabetic nephropathies

,

wet macular degeneration

,

,

,

retinal neovascularization

,

polypoidal choroidal vasculopathy

,

liver cirrhosis

,

,

diabetes complications

,

isolated systolic hypertension

,

systolic murmurs

,

,

left ventricular hypertrophy

,

,

glucose intolerance

,

,

chronic progressive multiple sclerosis

,

,

,

membranous glomerulonephritis

,

,

,

pathologic neovascularization

,

tick-borne encephalitis

,

,

,

,

renal replacement therapy

,

,

prehypertension

,

,

staphylococcal skin infections

,

,

,

neurobehavioral manifestations

,

heart transplantation

,

pituitary acth hypersecretion

,

cystic fibrosis

,

allergic bronchopulmonary aspergillosis

,

,

pituitary neoplasms

,

,

sexual infantilism

,

heart-lung transplantation

,

,

coronavirus infections

,

,

polyomavirus infections

,

retinal detachment

,

atrial fibrillation

,

iga glomerulonephritis

,

focal segmental glomerulosclerosis

,

nephrosclerosis

,

allergic conjunctivitis

,

reperfusion injury

,

delayed graft function

,

food hypersensitivity

,

islet cell adenoma

,

metabolic bone diseases

,

cryopyrin-associated periodic syndromes

,

,

,

,

immunosuppression therapy

,

angina pectoris

,

microvascular angina

,

spinal muscular atrophies of childhood

,

hematopoietic stem cell transplantation

,

secondary prevention

ischemic stroke

,

,

carotid stenosis

,

pathologic constriction

,

,

intracranial hemorrhages

,

,

,

myocardial infarction

,

,

cardiogenic shock

,

coronary artery disease

Antineoplaston a10

,

postpartum hemorrhage

,

myasthenia gravis

P2y purinoceptor 12

blood flow velocity

,

coronary circulation

,

pathologic processes

,

chronic obstructive pulmonary disease

,

obstructive lung diseases

,

,

ischemic stroke

,

,

,

kidney diseases

,

sickle cell anemia

,

,

respiratory tract infections

,

respiratory tract diseases

,

,

human influenza

,

community-acquired pneumonia

,

pancreatic ductal carcinoma

,

pancreatic neoplasms

,

,

graft rejection

,

cerebral infarction

,

coronary artery disease

,

acute coronary syndrome

,

myocardial infarction

,

,

coronary disease

,

myocardial ischemia

,

,

percutaneous coronary intervention

,

,

st elevation myocardial infarction

,

platelet aggregation

,

atrial fibrillation

,

cardiovascular diseases

,

,

,

unstable angina

,

inferior wall myocardial infarction

,

dual anti-platelet therapy

,

peripheral arterial disease

,

,

intracranial aneurysm

,

atherosclerosis

,

non-st elevated myocardial infarction

,

,

coronary stenosis

,

healthy volunteers/patients

,

chronic renal insufficiency

,

drug-eluting stents

,

,

,

endovascular procedures

,

peripheral vascular diseases

,

,

drug interactions

,

arteriosclerosis

,

,

,

cardiogenic shock

,

vascular diseases

,

ventricular remodeling

,

,

,

aortic valve stenosis

,

,

angina pectoris

,

platelet activation

,

platelet function tests

,

,

induced hypothermia

,

stomatognathic diseases

,

,

out-of-hospital cardiac arrest

,

migraine disorders

,

,

type 2 diabetes mellitus

,

,

thrombocytopenia

,

renal insufficiency

,

hematologic diseases

,

,

blood coagulation disorders

,

hemorrhagic stroke

,

hemostatic disorders

,

coagulation protein disorders

,

,

heart valve prosthesis

,

cerebral hemorrhage

,

subarachnoid hemorrhage

,

,

nervous system diseases

,

coronary thrombosis

,

drug resistance

,

,

disseminated intravascular coagulation

,

heart disease risk factors

,

,

systemic inflammatory response syndrome

,

,

postoperative hemorrhage

,

surgical blood loss

,

,

,

,

endomyocardial fibrosis

,

cerebrovascular disorders

,

stomach neoplasms

,

blood transfusion

,

arterial occlusive diseases

,

extracorporeal membrane oxygenation

,

drug-related side effects and adverse reactions

,

pharmacogenomic testing

,

cardiomyopathies

,

,

intracranial arteriosclerosis

,

diabetes mellitus

healthy volunteers/patients

Fluoroquinolone

healthy volunteers/patients

,

,

healthy volunteers/patients

,

myocardial ischemia

,

atherosclerosis

,

myocardial infarction

,

coronary artery disease

,

peripheral vascular diseases

,

diabetes mellitus

,

peripheral arterial disease

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