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The Medicines Company

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

All

Classification:

All

Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Angiox	Bivalirudin	2004-09-20	2028-2039	Acute coronary syndrome , Unstable angina
Ionsys	Fentanyl	2006-05-22	2024-2033	Neoplasms , Pain , Postoperative pain , Psychotic disorders

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

postoperative pain

venous thrombosis

,

healthy volunteers/patients

,

carotid artery diseases

,

coronary artery bypass

,

,

,

cardiovascular diseases

,

,

subarachnoid hemorrhage

,

,

intracranial aneurysm

,

endovascular procedures

,

aortic valve stenosis

,

transcatheter aortic valve replacement

,

hematologic diseases

,

cardiac surgical procedures

,

,

,

myocardial infarction

,

,

coronary artery disease

,

st elevation myocardial infarction

,

acute coronary syndrome

,

coronary disease

,

myocardial ischemia

,

percutaneous coronary intervention

,

,

inferior wall myocardial infarction

,

,

,

,

unstable angina

,

thrombocytopenia

,

non-st elevated myocardial infarction

,

,

,

balloon angioplasty coronary

,

respiratory distress syndrome

,

blood coagulation disorders

,

hemostatic disorders

,

angina pectoris

,

,

atherosclerosis

,

carotid stenosis

,

microvascular angina

,

respiratory insufficiency

acute coronary syndrome

,

thromboembolism

acute coronary syndrome

,

knee prosthesis

,

,

tendon injuries

,

,

tissue adhesions

,

hip osteoarthritis

,

,

,

high-risk pregnancy

,

intervertebral disc degeneration

,

,

multiple trauma

,

,

neoplasm metastasis

,

operative surgical procedures

,

urinary retention

,

,

patient satisfaction

,

,

physician-nurse relations

,

,

traumatic intracranial hemorrhage

,

,

,

,

pulmonary emphysema

,

,

spinal curvatures

,

critical illness

,

pituitary neoplasms

,

pituitary diseases

,

hereditary breast and ovarian cancer syndrome

,

spinal cord neoplasms

,

spinal neoplasms

,

squamous cell carcinoma

,

,

traumatic brain injuries

,

,

,

von willebrand diseases

,

,

,

hematologic neoplasms

,

,

hereditary hemorrhagic telangiectasia

,

,

,

hyperpigmentation

,

hemorrhagic shock

,

thrombocytopenia

,

transfusion reaction

,

coronary artery bypass

,

,

chronic renal insufficiency

,

kidney diseases

,

,

urinary bladder neoplasms

,

,

,

,

traumatic brain hemorrhage

,

pulmonary hypertension

,

lung transplantation

,

spinal dysraphism

,

,

intraoperative complications

,

aortic dissection

,

brain neoplasms

,

head and neck neoplasms

,

,

acute kidney injury

,

transcatheter aortic valve replacement

,

hereditary angioedemas

,

female genital neoplasms

,

,

,

obstetric labor

,

,

hematopoietic stem cell transplantation

,

,

subarachnoid hemorrhage

,

carotid artery diseases

,

spinal injuries

,

abdominal aortic aneurysm

,

,

aortic aneurysm

,

,

,

pancreatic neoplasms

,

hepatocellular carcinoma

,

,

,

femoracetabular impingement

,

,

surgical wound infection

,

,

,

,

,

,

agranulocytosis

,

feeding behavior

,

replacement arthroplasty shoulder

,

,

postpartum hemorrhage

,

surgical blood loss

,

postoperative hemorrhage

,

,

knee osteoarthritis

,

,

,

,

,

,

obstetric labor complications

,

wounds and injuries

,

postoperative pain

,

replacement arthroplasty knee

,

blood coagulation disorders

,

hemostatic disorders

,

placenta previa

,

,

uterine hemorrhage

,

blood transfusion

,

gastrointestinal hemorrhage

,

replacement arthroplasty hip

,

cerebral hemorrhage

,

,

,

,

,

subdural hematoma

,

,

,

drug-related side effects and adverse reactions

,

cardiac surgical procedures

,

subdural hematoma chronic

,

femoral fractures

,

,

,

,

,

,

,

rotator cuff injuries

,

,

breast neoplasms

,

cardiopulmonary bypass

,

coronary artery disease

,

,

postoperative complications

,

venous thrombosis

,

,

,

,

,

congenital abnormalities

,

congenital heart defects

,

,

,

,

liver cirrhosis

,

ovarian neoplasms

,

uterine myomectomy

,

anterior cruciate ligament reconstruction

,

,

cesarean section

,

thromboembolism

,

craniosynostoses

,

,

,

communicable diseases

,

healthy volunteers/patients

,

anterior cruciate ligament injuries

,

,

paranasal sinus diseases

,

shoulder impingement syndrome

,

prostatic neoplasms

,

,

,

nephrolithiasis

,

,

ovarian epithelial carcinoma

,

,

placenta accreta

,

spinal stenosis

,

,

,

femoral neck fractures

,

,

prostatic hyperplasia

,

hypersensitivity

,

,

,

pathologic dilatation

,

urologic diseases

,

,

orthognathic surgery

,

tooth extraction

,

pregnancy complications

,

pelvic organ prolapse

,

,

hemorrhagic stroke

,

,

,

stomach neoplasms

,

liver neoplasms

,

colonic neoplasms

,

intracranial hemorrhages

,

radius fractures

,

wrist fractures

,

venous thromboembolism

,

humeral fractures

,

,

,

opioid-related disorders

,

deficiency diseases

,

chronic urticaria

,

,

nasal obstruction

,

,

injection site reaction

,

,

cross infection

,

wound infection

,

,

,

,

,

colorectal neoplasms

,

uterine inertia

,

staghorn calculi

,

myocardial infarction

,

pulmonary embolism

,

,

,

,

hemiarthroplasty

,

arteriovenous fistula

,

,

pathologic constriction

,

gynecologic surgical procedures

,

,

,

,

,

pancreaticoduodenectomy

,

,

biliary tract surgical procedures

,

,

,

dupuytren contracture

,

,

,

,

,

esophageal neoplasms

,

duodenal neoplasms

,

heart valve diseases

,

prospective studies

,

randomized controlled trials as topic

,

eyelid diseases

,

,

shoulder fractures

,

shoulder injuries

,

contraceptive devices

,

autoimmune diseases

,

intravenous administration

,

,

,

,

,

,

hyperaldosteronism

,

pulmonary arterial hypertension

,

urinary tract infections

,

,

sleep initiation and maintenance disorders

,

cardiac arrhythmias

,

,

,

,

,

blood platelet disorders

,

,

heterotopic ossification

,

coronary disease

,

myocardial ischemia

,

coronavirus infections

,

,

mucocutaneous lymph node syndrome

,

hyperphosphatemia

,

bronchopulmonary dysplasia

,

adrenal insufficiency

,

,

coagulation protein disorders

,

attention deficit disorder with hyperactivity

,

musculoskeletal diseases

,

,

rheumatoid arthritis

,

replacement arthroplasty

,

respiratory tract infections

,

,

migraine disorders

,

,

,

bacterial infections

,

intraabdominal infections

,

healthcare-associated pneumonia

,

methicillin-resistant staphylococcus aureus

,

,

staphylococcal infections

,

,

,

general anesthesia

,

,

,

gram-negative bacterial infections

,

,

bacterial meningitis

,

,

central nervous system infections

,

neuromuscular blockade

,

,

,

cytomegalovirus retinitis

,

adenoviridae infections

,

port-wine stain

,

,

,

capillary hemangioma

,

,

bipolar disorder

,

autistic disorder

,

,

treatment-resistant schizophrenia

,

potassium deficiency

,

,

iron-deficiency anemia

,

iron deficiencies

,

cytoreduction surgical procedures

,

primary graft dysfunction

,

intervertebral disc displacement

,

,

liver transplantation

,

congenital hip dislocation

,

developmental dysplasia of the hip

,

femur head necrosis

,

,

acute lung injury

,

retinal diseases

,

factor xi deficiency

,

closed fractures

,

orthopedic procedures

,

erythrocyte transfusion

,

neurosurgical procedures

,

lacrimal duct obstruction

,

off-pump coronary artery bypass

,

spinal cord diseases

,

spinal cord compression

,

hematologic diseases

,

recreational drug use

,

,

peptic ulcer hemorrhage

,

osteogenesis imperfecta

,

skin pigmentation

,

,

obstetric delivery

,

,

obstetrical anesthesia

,

abruptio placentae

,

prolonged pregnancy

,

,

transurethral resection of prostate

,

vaginal hysterectomy

,

percutaneous nephrolithotomy

,

pigmentation disorders

,

vascular diseases

,

,

bariatric surgery

,

cardiovascular surgical procedures

,

lens subluxation

,

joint dislocations

,

fracture dislocation

,

elbow fractures

,

dermatofibrosarcoma

,

spontaneous fractures

,

thoracic surgical procedures

,

autologous blood transfusion

,

,

spinal diseases

,

,

,

,

retinal detachment

,

diabetic retinopathy

,

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

myeloid leukemia

,

,

renal insufficiency

,

,

spinal anesthesia

,

Antineoplaston a10

therapeutic equivalency

,

psychotic disorders

,

,

autism spectrum disorder

,

,

respiratory aspiration

,

acquired immunodeficiency syndrome

,

,

irritable bowel syndrome

,

migraine disorders

,

pharmacokinetics

,

inflammatory bowel diseases

,

intestinal diseases

,

,

,

,

,

alcohol drinking

,

neoplasm metastasis

,

,

pathologic dilatation

,

asymptomatic diseases

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

invasive hydatidiform mole

,

reperfusion injury

,

,

hepatic insufficiency

,

biological availability

,

food diet and nutrition

,

,

tissue adhesions

,

psychomotor disorders

,

glomerular filtration rate

,

,

cutaneous lupus erythematosus

,

escherichia coli infections

,

vascular system injuries

,

persian gulf syndrome

,

occupational diseases

,

drug delivery systems

,

severity of illness index

,

metabolic side effects of drugs and substances

,

pharmacological phenomena

,

,

atrophic vaginitis

,

,

,

,

,

myositis ossificans

,

root resorption

,

,

,

,

,

,

posterior uveitis

,

henipavirus infections

,

food-drug interactions

,

fecal incontinence

,

tick-borne encephalitis

,

,

,

urologic neoplasms

,

musculoskeletal manipulations

,

bullous pemphigoid

,

hemolytic anemia autoimmune

,

hemolytic anemia

,

psoriatic arthritis

,

,

pyloric stenosis

,

gastric outlet obstruction

,

,

skin transplantation

,

west nile fever

,

shy-drager syndrome

,

multiple system atrophy

,

mouth neoplasms

,

,

marburg virus disease

,

vesicular stomatitis

,

interstitial lung diseases

,

rotator cuff tear arthropathy

,

,

haemophilus infections

,

haemophilus meningitis

,

hidradenitis suppurativa

,

,

,

escherichia coli

,

arterial pressure

,

drug interactions

,

,

ischemic preconditioning

,

,

,

,

chronic obstructive pulmonary disease

,

hypersensitivity

,

,

,

,

head and neck neoplasms

,

,

colorectal neoplasms

,

,

non-hodgkin lymphoma

,

,

chronic kidney failure

,

pediatric obesity

,

,

,

stomach neoplasms

,

obstructive lung diseases

,

sleep apnea syndromes

,

,

musculoskeletal diseases

,

myeloid leukemia

,

esophageal neoplasms

,

colonic neoplasms

,

atherosclerosis

,

,

brain neoplasms

,

,

anorexia nervosa

,

acute lung injury

,

,

postoperative complications

,

,

ovarian neoplasms

,

,

hematologic neoplasms

,

renal cell carcinoma

,

human influenza

,

,

,

squamous cell carcinoma

,

squamous cell carcinoma of head and neck

,

,

,

central nervous system neoplasms

,

,

,

,

obstructive sleep apnea

,

non-alcoholic fatty liver disease

,

accidental injuries

,

,

endometrial neoplasms

,

,

ovarian epithelial carcinoma

,

deglutition disorders

,

,

,

pain management

,

,

,

mantle-cell lymphoma

,

kidney neoplasms

,

squamous cell neoplasms

,

triple negative breast neoplasms

,

,

,

,

,

,

,

marijuana abuse

,

,

temporomandibular joint disorders

,

temporomandibular joint dysfunction syndrome

,

,

suicidal ideation

,

oligodendroglioma

,

carpal tunnel syndrome

,

physical therapy modalities

,

falciparum malaria

,

thyroid neoplasms

,

papillary thyroid cancer

,

thyroid diseases

,

b-cell lymphoma

,

cocaine-related disorders

,

bcr-abl positive chronic myelogenous leukemia

,

,

bile duct neoplasms

,

,

malignant fibrous histiocytoma

,

systemic scleroderma

,

diffuse scleroderma

,

malignant mesothelioma

,

crimean hemorrhagic fever

,

viral hemorrhagic fevers

,

allergic rhinitis seasonal

,

,

muscular diseases

,

adenoviridae infections

,

intestinal neoplasms

,

,

food hypersensitivity

,

tobacco smoking

,

pregnancy complications

,

colonic diseases

,

intracranial aneurysm

,

diabetic nephropathies

,

cartilage diseases

,

kidney transplantation

,

primitive neuroectodermal tumors

,

neuroectodermal tumors

,

neuroendocrine carcinoma

,

pituitary neoplasms

,

pituitary diseases

,

small cell lung carcinoma

,

,

,

,

health risk behaviors

,

,

cardiac surgical procedures

,

graft vs host disease

,

follicular adenocarcinoma

,

soft tissue infections

,

staphylococcal infections

,

,

,

treatment-resistant depressive disorder

,

severe acute respiratory syndrome

,

myelomonocytic leukemia juvenile

,

cholangiocarcinoma

,

,

dermatomyositis

,

myelomonocytic leukemia chronic

,

refractory anemia with excess of blasts

,

refractory anemia

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

adenosquamous carcinoma

,

,

infectious mononucleosis

,

capsule opacification

,

,

alopecia areata

,

,

,

,

,

,

hemangiosarcoma

,

synovial sarcoma

,

neurofibrosarcoma

,

nerve sheath neoplasms

,

,

juvenile myoclonic epilepsy

,

peritoneal dialysis

,

inappropriate adh syndrome

,

,

speech sound disorder

,

essential tremor

,

,

magnetic resonance imaging

,

myocardial perfusion imaging

,

oropharyngeal neoplasms

,

diastolic heart failure

,

immediate hypersensitivity

,

fuchs' endothelial dystrophy

,

hereditary corneal dystrophies

,

breakthrough pain

,

,

,

neurofibromatoses

,

,

,

autoimmune pancreatitis

,

,

diffuse intrinsic pontine glioma

,

pneumococcal infections

,

bladder exstrophy

,

subarachnoid hemorrhage

,

clostridioides difficile

,

,

alcohol-related disorders

,

unknown primary neoplasms

,

vulvar neoplasms

,

merkel cell carcinoma

,

islet cell carcinoma

,

waldenstrom macroglobulinemia

,

bronchiolo-alveolar adenocarcinoma

,

,

,

,

adrenocortical carcinoma

,

headache disorders

,

cluster headache

,

primary headache disorders

,

trigeminal autonomic cephalalgias

,

hyperemesis gravidarum

,

,

,

paranasal sinus diseases

,

biliary atresia

,

,

cardio-renal syndrome

,

childhood-onset fluency disorder

,

cardiopulmonary bypass

,

coronary artery bypass

,

spinal stenosis

,

,

,

breast neoplasms

,

,

,

prostatic neoplasms

,

,

parkinson disease

,

,

non-small-cell lung carcinoma

,

substance-related disorders

,

,

,

urinary incontinence

,

,

metabolic syndrome

,

,

,

acute kidney injury

,

uterine cervical neoplasms

,

,

,

,

opioid-related disorders

,

respiratory insufficiency

,

renal insufficiency

,

attention deficit disorder with hyperactivity

,

,

myocardial infarction

,

,

respiratory distress syndrome

,

immunologic deficiency syndromes

,

,

allergic rhinitis

,

,

traumatic brain injuries

,

,

myeloid leukemia acute

,

newborn respiratory distress syndrome

,

nervous system diseases

,

generalized anxiety disorder

,

hyperlipidemias

,

critical illness

,

,

,

diabetic neuropathies

,

,

open-angle glaucoma

,

,

acute coronary syndrome

,

liver neoplasms

,

,

,

stress urinary incontinence

,

overactive urinary bladder

,

precursor cell lymphoblastic leukemia-lymphoma

,

myelodysplastic syndromes

,

,

lymphoid leukemia

,

blood coagulation disorders

,

hemostatic disorders

,

,

executive function

,

,

pathologic constriction

,

systemic lupus erythematosus

,

,

postpartum hemorrhage

,

,

problem behavior

,

laparoscopic cholecystectomy

,

thrombocytopenic purpura

,

,

myoclonic epilepsies

,

urinary bladder neoplasms

,

,

hepatocellular carcinoma

,

,

b-cell chronic lymphocytic leukemia

,

,

macular degeneration

,

choroidal neovascularization

,

pathologic neovascularization

,

nasopharyngeal neoplasms

,

brain concussion

,

,

,

,

female genital diseases

,

gastrointestinal neoplasms

,

iron deficiencies

,

erectile dysfunction

,

gastroesophageal reflux

,

brain stem neoplasms

,

,

,

coronavirus infections

,

ocular hypertension

,

lennox gastaut syndrome

,

bronchiolitis obliterans

,

,

bronchiolitis obliterans syndrome

,

transitional cell carcinoma

,

neuroendocrine tumors

,

carcinoid tumor

,

malignant carcinoid syndrome

,

serotonin syndrome

,

st elevation myocardial infarction

,

myeloproliferative disorders

,

primary myelofibrosis

,

optic nerve glioma

,

nasopharyngeal carcinoma

,

,

biliary tract diseases

,

,

genital diseases

,

placenta previa

,

craniosynostoses

,

iron-deficiency anemia

,

attention deficit and disruptive behavior disorders

,

streptococcal infections

,

inferior wall myocardial infarction

,

papillomavirus infections

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

agammaglobulinemia

,

post-concussion syndrome

,

thrombocytopenic purpura idiopathic

,

primary immunodeficiency diseases

,

soft tissue injuries

,

respiratory tract infections

,

autonomic nervous system diseases

,

severe acute respiratory syndrome-related coronavirus

,

bacterial infections

,

methicillin-resistant staphylococcus aureus

,

staphylococcal skin infections

,

infectious skin diseases

,

bacterial skin diseases

,

,

,

thrombotic thrombocytopenic purpura

,

ureteral neoplasms

,

,

non-st elevated myocardial infarction

,

beta-thalassemia

,

,

,

performance anxiety

,

patent ductus arteriosus

,

allergic rhinitis perennial

,

,

diabetic ketoacidosis

,

,

multiple symmetrical lipomatosis

,

,

dietary supplements

,

myasthenia gravis

,

urinary fistula

,

,

,

,

viral hepatitis human

,

digestive system neoplasms

,

gastrointestinal stromal tumors

,

,

lower urinary tract symptoms

,

coagulation protein disorders

,

,

bile duct diseases

,

urge urinary incontinence

,

phobic disorders

,

mucocutaneous lymph node syndrome

,

,

hemorrhagic shock

,

,

,

adrenal insufficiency

,

geriatric assessment

,

brain hypoxia-ischemia

,

primary dysautonomias

,

healthy volunteers/patients

,

,

diabetes mellitus

,

,

,

wounds and injuries

,

,

type 2 diabetes mellitus

,

,

,

cognitive dysfunction

,

depressive disorder

,

knee osteoarthritis

,

anxiety disorders

,

postoperative pain

,

,

,

,

cardiovascular diseases

,

mental disorders

,

alzheimer disease

,

kidney diseases

,

,

,

type 1 diabetes mellitus

,

,

,

,

spinal cord injuries

,

,

,

,

,

communicable diseases

,

multiple myeloma

,

plasma cell neoplasms

,

pancreatic neoplasms

,

chronic renal insufficiency

,

,

coronary artery disease

,

post-traumatic stress disorders

,

multiple sclerosis

,

myofascial pain syndromes

,

,

major depressive disorder

,

premature birth

,

myocardial ischemia

,

bipolar disorder

,

rheumatoid arthritis

,

atrial fibrillation

,

sleep initiation and maintenance disorders

,

,

tobacco use disorder

,

,

,

,

,

coronary disease

,

,

ischemic stroke

,

,

somatoform disorders

,

,

,

,

smoking cessation

,

traumatic stress disorders

,

,

,

,

cholecystolithiasis

,

,

cardiomyopathies

,

,

,

,

physical fitness

,

,

,

postoperative nausea and vomiting

,

drug-related side effects and adverse reactions

,

,

cerebral infarction

,

,

,

hypercholesterolemia

,

wound infection

,

atopic dermatitis

,

bronchopulmonary dysplasia

,

,

altitude sickness

,

pulmonary hypertension

,

metabolic bone diseases

,

,

,

,

rotator cuff injuries

,

artificial respiration

,

portal hypertension

,

clostridium infections

,

anesthesia and analgesia

,

disease susceptibility

,

,

video-assisted thoracic surgery

,

,

vascular diseases

,

essential hypertension

,

neuromuscular blockade

,

,

,

,

local anesthesia

,

,

,

obstetric labor complications

,

pulmonary arterial hypertension

,

general anesthesia

,

,

,

,

helicobacter infections

,

,

surgical wound infection

,

humeral fractures

,

,

aortic dissection

,

,

venous thrombosis

,

intravenous anesthesia

,

arteriovenous fistula

,

,

,

,

liver cirrhosis

,

femoral fractures

,

,

,

,

,

osteoporotic fractures

,

neurosurgical procedures

,

polypoidal choroidal vasculopathy

,

pulmonary embolism

,

,

antiphospholipid syndrome

,

,

intravenous substance abuse

,

,

postoperative cognitive complications

,

,

duration of therapy

,

,

,

vocal cord paralysis

,

systolic heart failure

,

systolic murmurs

,

,

giant cell arteritis

,

polymyalgia rheumatica

,

blood transfusion

,

,

bilateral hearing loss

,

,

uterine myomectomy

,

thrombophlebitis

,

injection site reaction

,

,

trematode infections

,

pancreatic diseases

,

,

,

,

,

,

psychological stress

,

,

,

autistic disorder

,

feeding behavior

,

sedentary behavior

,

,

,

health behavior

,

congenital abnormalities

,

chronic disease

,

,

peripheral nervous system diseases

,

neurologic gait disorders

,

mobility limitation

,

prediabetic state

,

physiological stress

,

,

,

feeding and eating disorders

,

heart disease risk factors

,

psychological distress

,

male breast neoplasms

,

,

insulin resistance

,

exercise tolerance

,

,

,

pervasive child development disorders

,

sleep wake disorders

,

muscle weakness

,

,

congenital heart defects

,

emotional regulation

,

transcranial direct current stimulation

,

,

,

psychological burnout

,

polycystic ovary syndrome

,

glucose intolerance

,

musculoskeletal pain

,

psychological adaptation

,

neurodevelopmental disorders

,

tension-type headache

,

psychological resilience

,

addictive behavior

,

plantar fasciitis

,

,

,

periodontal diseases

,

,

tourette syndrome

,

olfaction disorders

,

central nervous system sensitization

,

postpartum depression

,

,

patient satisfaction

,

,

,

,

,

sexually transmitted diseases

,

,

cesarean section

,

,

,

,

cerebral hemorrhage

,

cardiometabolic risk factors

,

gastrointestinal microbiome

,

,

exercise therapy

,

microcirculation

,

oxidative stress

,

,

,

dentin sensitivity

,

,

,

muscle diastasis

,

,

memory disorders

,

cognition disorders

,

gestational diabetes

,

ventilator-associated pneumonia

,

hip osteoarthritis

,

female infertility

,

joint instability

,

,

,

respiration disorders

,

post-acute covid-19 syndrome

,

spondylarthritis

,

fetal growth retardation

,

,

muscle spasticity

,

bariatric surgery

,

,

resistance training

,

body weight changes

,

periapical periodontitis

,

child development

,

,

vascular stiffness

,

,

,

,

,

binge-eating disorder

,

breast cancer lymphedema

,

,

telerehabilitation

,

multiple chronic conditions

,

,

postural balance

,

newborn infant diseases

,

,

muscular atrophy

,

,

conduction anesthesia

,

,

,

arterial occlusive diseases

,

retinal diseases

,

diabetic retinopathy

,

vitamin d deficiency

,

takotsubo cardiomyopathy

,

bronchial hyperreactivity

,

basal cell carcinoma

,

basal cell neoplasms

,

carbohydrate metabolism

,

environmental biomarkers

,

,

trauma and stressor related disorders

,

obesity hypoventilation syndrome

,

hypoventilation

,

,

,

,

medication adherence

,

cigarette smoking

,

breast carcinoma in situ

,

patellofemoral pain syndrome

,

impulsive behavior

,

eosinophilic esophagitis

,

anterior cruciate ligament injuries

,

,

short-term memory

,

cumulative trauma disorders

,

,

migraine without aura

,

ultrasonography

,

,

neurologic manifestations

,

rectal neoplasms

,

thoracic neoplasms

,

tobacco use cessation

,

peripheral arterial disease

,

,

nephrolithiasis

,

,

pregnancy in adolescence

,

intervertebral disc degeneration

,

intervertebral disc displacement

,

joint dislocations

,

cardiopulmonary resuscitation

,

recreational drug use

,

,

,

pancreatic ductal carcinoma

,

autoimmune diseases

,

respiratory tract diseases

,

,

,

velopharyngeal insufficiency

,

,

ankylosing spondylitis

,

movement disorders

,

articular range of motion

,

intracranial hypertension

,

replacement arthroplasty knee

,

ureteral diseases

,

,

,

preoperative exercise

,

duchenne muscular dystrophy

,

muscular dystrophies

,

axial spondyloarthritis

,

aortic valve stenosis

,

aortic valve insufficiency

,

dilated cardiomyopathy

,

,

,

,

,

muscle strength

,

,

,

,

,

,

,

,

sickle cell anemia

,

sleep deprivation

,

carcinoma in situ

,

,

,

,

pneumoperitoneum

,

,

,

,

electroencephalography

,

disease progression

,

,

female genital neoplasms

,

,

,

abdominal obesity

,

,

lens subluxation

,

prehypertension

,

cardiac arrhythmias

,

,

,

,

univentricular heart

,

gallbladder diseases

,

,

,

replacement arthroplasty hip

,

,

cerebrovascular disorders

,

,

induced abortion

,

developmental disabilities

,

occupational stress

,

reflex sympathetic dystrophy

,

,

body composition

,

metabolic diseases

,

athletic injuries

,

rheumatic diseases

,

collagen diseases

,

,

,

,

,

,

,

,

vulvovaginal candidiasis

,

,

,

parent-child relations

,

radius fractures

,

wrist fractures

,

inguinal hernia

,

carotid stenosis

,

heat stress disorders

,

pelvic floor disorders

,

juvenile arthritis

,

,

,

,

,

,

,

mother-child relations

,

dental pulp necrosis

,

vascular access devices

,

spinal anesthesia

,

hyperbaric oxygenation

,

,

cardiorespiratory fitness

,

ulcerative colitis

,

,

,

adenomatous polyposis coli

,

surgical blood loss

,

laryngeal edema

,

airway obstruction

,

,

,

photochemotherapy

,

chronobiology disorders

,

central serous chorioretinopathy

,

,

hyperparathyroidism

,

primary hyperparathyroidism

,

endocrine gland neoplasms

,

thymus neoplasms

,

multiple endocrine neoplasia type 1

,

parathyroid diseases

,

drug hypersensitivity

,

,

deprescriptions

,

retinal vein occlusion

,

end stage liver disease

,

acute-on-chronic liver failure

,

intravitreal injections

,

,

,

frontotemporal dementia

,

primary progressive aphasia

,

pick disease of the brain

,

essential thrombocythemia

,

polycythemia vera

,

,

,

risk reduction behavior

,

growth disorders

,

,

premature obstetric labor

,

,

predictive value of tests

,

chronic periodontitis

,

postural orthostatic tachycardia syndrome

,

,

facial neuralgia

,

,

dental care for children

,

,

glucose metabolism disorders

,

,

emotional adjustment

,

cerebral ventriculitis

,

hoarding disorder

,

normal pressure hydrocephalus

,

high-risk pregnancy

,

hereditary congenital and neonatal diseases and abnormalities

,

arteriovenous malformations

,

congenital cystic adenomatoid malformation of lung

,

psychological trauma

,

,

meibomian gland dysfunction

,

war-related injuries

,

sinus arrhythmia

,

,

respiratory sinus arrhythmia

,

,

,

,

,

psychological sexual dysfunctions

,

central venous pressure

,

,

filarial elephantiasis

,

,

,

,

,

angina pectoris

,

,

psychomotor agitation

,

,

unstable angina

,

,

,

,

neurocognitive disorders

,

acupuncture therapy

,

ventilator weaning

,

neonatal jaundice

,

hyperbilirubinemia

,

,

urinary tract infections

,

signs and symptoms

,

pathologic processes

,

liver transplantation

,

penile induration

,

,

heart transplantation

,

abdominal aortic aneurysm

,

aortic aneurysm

,

aortic diseases

,

pulmonary infarction

,

self stimulation

,

systemic inflammatory response syndrome

,

implantable defibrillators

,

oppositional defiant disorder

,

,

,

urogenital neoplasms

,

male genital diseases

,

prostatic diseases

,

male genital neoplasms

,

psychotic affective disorders

,

,

multidrug-resistant tuberculosis

,

spondylolisthesis

,

fibrocystic breast disease

,

congenital hip dislocation

,

hip dislocation

,

developmental dysplasia of the hip

,

diabetes complications

,

sensitivity training groups

,

,

umbilical hernia

,

,

,

periodontal pocket

,

free tissue flaps

,

,

,

intratracheal intubation

,

,

,

affective symptoms

,

,

ocular motility disorders

,

,

,

,

,

,

fine-needle biopsy

,

vaccination refusal

,

attitude to health

,

,

,

radiation exposure

,

nervous system neoplasms

,

,

,

,

,

occupational therapy

,

,

ocular albinism

,

gingival recession

,

pain measurement

,

,

postmenopausal osteoporosis

,

hypertrophic cardiomyopathy

,

,

vascular malformations

,

pericardial effusion

,

,

emphysematous pyelonephritis

,

ectopic pregnancy

,

premature cardiac complexes

,

,

,

intraabdominal infections

,

nutrition therapy

,

tetralogy of fallot

,

,

,

pelvic organ prolapse

,

,

leriche syndrome

,

,

,

contraception behavior

,

attempted suicide

,

mitochondrial diseases

,

bronchoalveolar lavage

,

hyperlipoproteinemia type i

,

hodgkin disease

,

aplastic anemia

,

shoulder impingement syndrome

,

,

shoulder injuries

,

,

nocturnal enuresis

,

lobular carcinoma

,

,

intraductal carcinoma noninfiltrating

,

phenylketonurias

,

stroke rehabilitation

,

,

,

middle cerebral artery infarction

,

acute cholecystitis

,

acalculous cholecystitis

,

oxygen inhalation therapy

,

,

,

interdisciplinary communication

,

,

feasibility studies

,

bone marrow transplantation

,

early detection of cancer

,

,

rumination syndrome

,

,

,

iliotibial band syndrome

,

barrett esophagus

,

,

adolescent development

,

schizophrenia spectrum and other psychotic disorders

,

,

voice disorders

,

vocal cord dysfunction

,

patient compliance

,

social psychology

,

,

myofascial release therapy

,

spinal injuries

,

,

,

pancreaticoduodenectomy

,

task performance and analysis

,

focal nodular hyperplasia

,

sexual behavior

,

bacillary dysentery

,

shigella sonnei

,

,

seborrheic dermatitis

,

,

edentulous mouth

,

compassion fatigue

,

gastrointestinal diseases

,

,

digestive system diseases

,

patient discharge

,

,

hematopoietic stem cell transplantation

,

meconium aspiration syndrome

,

ventricular tachycardia

,

gaucher disease

,

peptic esophagitis

,

brain infarction

,

,

closed fractures

,

spontaneous abortion

,

habitual abortion

,

,

,

,

genetic markers

,

muscle stretching exercises

,

,

median neuropathy

,

intracranial vasospasm

,

four-dimensional computed tomography

,

electric impedance

,

choledocholithiasis

,

hypertensive intracranial hemorrhage

,

,

craniofacial dysostosis

,

carotid endarterectomy

,

,

neurobehavioral manifestations

,

,

endomyocardial fibrosis

,

male infertility

,

intracytoplasmic sperm injections

,

epidural analgesia

,

,

,

gender dysphoria

,

hypoparathyroidism

,

interpersonal relations

,

infectious arthritis

,

may-thurner syndrome

,

complex regional pain syndromes

,

radiofrequency ablation

,

,

,

,

,

hemolytic-uremic syndrome

,

water intoxication

,

,

,

,

peripheral catheterization

,

transfusion reaction

,

postoperative hemorrhage

,

smoking reduction

,

,

uterine hemorrhage

,

vaccination hesitancy

,

disorders of excessive somnolence

,

hemorrhagic stroke

,

blood pressure monitors

,

papillomaviridae

,

uterine cervical dysplasia

,

,

foot deformities

,

child nutrition disorders

,

orthostatic intolerance

,

myocardial ischemic preconditioning

,

,

interstitial cystitis

,

,

venous insufficiency

,

therapeutic alliance

,

,

supraventricular tachycardia

,

,

,

urinary bladder diseases

,

body temperature changes

,

consciousness disorders

,

facioscapulohumeral muscular dystrophy

,

caregiver burden

,

anorectal malformations

,

chronic bronchitis

,

,

,

uterine diseases

,

stress fractures

,

chronic brain injury

,

,

,

,

,

asperger syndrome

,

professional burnout

,

dietary proteins

,

neurological rehabilitation

,

low cardiac output

,

hemodynamic monitoring

,

hospitalization

,

prodromal symptoms

,

,

life change events

,

arrhythmogenic right ventricular dysplasia

,

family characteristics

,

urethral stricture

,

lichen sclerosus et atrophicus

,

,

cholecystectomy

,

odontogenic cysts

,

,

,

motion sickness

,

intracranial hemorrhages

,

low-level light therapy

,

surgical amputation

,

,

ataxia telangiectasia

,

cerebellar ataxia

,

,

diurnal enuresis

,

,

,

self-injurious behavior

,

myocardial revascularization

,

arteriosclerosis

,

,

machine learning

,

patient acceptance of health care

,

laughter therapy

,

postoperative period

,

,

chronic hepatitis b

,

dissociative disorders

,

alcohol abstinence

,

cavernous hemangioma central nervous system

,

corneal transplantation

,

dental implants

,

dental prosthesis

,

,

dna repair-deficiency disorders

,

xeroderma pigmentosum

,

trichothiodystrophy syndromes

,

,

cockayne syndrome

,

attitudes health knowledge practice

,

,

localized scleroderma

,

,

calcinosis cutis

,

forearm injuries

,

suicide prevention

,

familial primary pulmonary hypertension

,

facial injuries

,

acquired nose deformities

,

,

postpartum period

,

,

pregnancy-induced hypertension

,

,

transverse myelitis

,

,

,

continuous positive airway pressure

,

intermittent positive-pressure ventilation

,

family relations

,

femoral neck fractures

,

maternal behavior

,

gastrointestinal endoscopy

,

conscious sedation

,

transient ischemic attack

,

,

,

,

,

asphyxia neonatorum

,

,

posterior tibial tendon dysfunction

,

geriatric psychiatry

,

medically unexplained symptoms

,

ankle fractures

,

,

spinal muscular atrophy

,

femoracetabular impingement

,

psychological well-being

,

abdominal neoplasms

,

skull base neoplasms

,

cytokine release syndrome

,

whiplash injuries

,

,

social isolation

,

,

sprains and strains

,

,

personal satisfaction

,

,

carbon monoxide poisoning

,

,

,

,

body temperature regulation

,

internet addiction disorder

,

tooth discoloration

,

choledochal cyst

,

,

magnetic resonance spectroscopy

,

,

penetrating wounds

,

needlestick injuries

,

,

,

,

urinary calculi

,

biphenotypic leukemia acute

,

philadelphia chromosome

,

neurogenic bowel

,

extrinsic allergic alveolitis

,

brachial plexus block

,

,

elective surgical procedures

,

preoperative period

,

heat-shock response

,

orthostatic hypotension

,

neuroinflammatory diseases

,

anesthesia recovery period

,

,

,

cystic fibrosis

,

,

subdural hematoma

,

subdural hematoma chronic

,

,

clinical trials as topic

,

postherpetic neuralgia

,

,

pulmonary edema

,

digestive system endoscopy

,

,

,

esophageal and gastric varices

,

,

cognitive behavioral therapy

,

bone malalignment

,

adenocarcinoma of lung

,

peripheral nerve injuries

,

nerve regeneration

,

hematologic tests

,

medial tibial stress syndrome

,

anterior cruciate ligament reconstruction

,

,

tibial meniscus injuries

,

dental enamel hypoplasia

,

molar hypomineralization

,

obstructive jaundice

,

femoral neuropathy

,

intraoperative complications

,

thoracic surgical procedures

P2y purinoceptor 12

healthy volunteers/patients

,

pharmacokinetics

,

therapeutic equivalency

,

renal insufficiency

,

,

biological availability

,

drug interactions

,

blood flow velocity

,

coronary circulation

,

,

chronic kidney failure

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

arteriovenous fistula

,

,

vascular patency

,

abdominal aortic aneurysm

,

,

aortic aneurysm

,

,

sickle cell anemia

,

,

ischemic stroke

,

,

transient ischemic attack

,

percutaneous coronary intervention

,

atherosclerosis

,

,

drug-related side effects and adverse reactions

,

intracranial arteriosclerosis

,

arteriosclerosis

,

coronary artery disease

,

acute coronary syndrome

,

coronary disease

,

myocardial ischemia

,

myocardial infarction

,

,

,

cardiovascular diseases

,

diabetes mellitus

,

type 2 diabetes mellitus

,

,

st elevation myocardial infarction

,

peripheral arterial disease

,

,

,

inferior wall myocardial infarction

,

,

retinal diseases

,

wounds and injuries

,

migraine disorders

,

,

non-st elevated myocardial infarction

,

,

no-reflow phenomenon

,

vascular diseases

,

arterial occlusive diseases

,

intermittent claudication

,

ankle brachial index

,

atherosclerotic plaque

,

postpartum hemorrhage

acute coronary syndrome

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