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Company ReportsThe Medicines Company

The Medicines Company

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

All

Classification:

All

Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Angiox	Bivalirudin	2004-09-20	2028-2039	Acute coronary syndrome , Unstable angina
Ionsys	Fentanyl	2006-05-22	2024-2033	Neoplasms , Pain , Postoperative pain , Psychotic disorders

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

,

,

paroxysmal dyspnea

venous thrombosis

,

healthy volunteers/patients

,

carotid artery diseases

,

coronary artery bypass

,

,

,

cardiovascular diseases

,

,

subarachnoid hemorrhage

,

,

intracranial aneurysm

,

endovascular procedures

,

aortic valve stenosis

,

transcatheter aortic valve replacement

,

hematologic diseases

,

cardiac surgical procedures

,

,

,

myocardial infarction

,

,

coronary artery disease

,

st elevation myocardial infarction

,

acute coronary syndrome

,

coronary disease

,

myocardial ischemia

,

percutaneous coronary intervention

,

,

inferior wall myocardial infarction

,

,

,

,

unstable angina

,

thrombocytopenia

,

non-st elevated myocardial infarction

,

,

,

balloon angioplasty coronary

,

respiratory distress syndrome

,

blood coagulation disorders

,

hemostatic disorders

,

angina pectoris

,

,

atherosclerosis

,

carotid stenosis

,

microvascular angina

,

respiratory insufficiency

,

,

chronic hepatitis b

,

communicable diseases

,

,

parkinson disease

,

parkinsonian disorders

,

movement disorders

,

,

,

giant cell arteritis

,

polymyalgia rheumatica

,

chronic renal insufficiency

,

,

pituitary acth hypersecretion

,

acth-secreting pituitary adenoma

,

graft vs host disease

,

,

hodgkin disease

,

mantle-cell lymphoma

,

b-cell lymphoma

,

type 1 diabetes mellitus

,

,

,

myelodysplastic syndromes

,

thrombocytopenia

,

,

,

,

retinal vein occlusion

,

vision disorders

,

,

macular degeneration

,

breast neoplasms

,

thrombocytopenic purpura idiopathic

,

thrombocytopenic purpura

,

,

juvenile arthritis

,

,

kidney diseases

,

myocardial infarction

,

,

inferior wall myocardial infarction

,

organ transplantation

,

wet macular degeneration

,

neoplasm metastasis

,

graft rejection

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

,

non-alcoholic fatty liver disease

,

,

postoperative pain

,

,

choroidal neovascularization

,

pathologic neovascularization

,

chronic kidney failure

,

renal insufficiency

,

liver transplantation

,

kidney transplantation

,

,

,

,

ankylosing spondylitis

,

spondylarthritis

,

,

liver cirrhosis

,

,

atrial fibrillation

acute coronary syndrome

,

thromboembolism

Sodium chloride

healthy volunteers/patients

,

,

major depressive disorder

,

depressive disorder

,

prostatic hyperplasia

,

,

knee osteoarthritis

,

,

,

,

carpal tunnel syndrome

,

,

premature birth

,

premature ejaculation

,

,

,

,

penile induration

,

,

thoracic outlet syndrome

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

musculoskeletal pain

,

systemic lupus erythematosus

,

,

,

,

dystonic disorders

,

,

myofascial pain syndromes

,

,

somatoform disorders

,

,

parkinson disease

,

temporomandibular joint disorders

,

,

temporomandibular joint dysfunction syndrome

,

,

systemic scleroderma

,

raynaud disease

,

localized scleroderma

,

diffuse scleroderma

,

urinary bladder diseases

,

multiple sclerosis

,

neurogenic urinary bladder

,

,

breast neoplasms

,

,

postoperative pain

,

breast diseases

,

hereditary breast and ovarian cancer syndrome

,

,

patellofemoral pain syndrome

,

,

chronic disease

,

overactive urinary bladder

,

muscle spasticity

,

,

migraine disorders

,

urinary incontinence

,

,

,

interstitial cystitis

,

,

,

,

wounds and injuries

,

,

,

,

,

graves ophthalmopathy

,

spinal cord injuries

,

microbial drug resistance

,

,

,

postoperative nausea and vomiting

,

bariatric surgery

,

,

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

,

herpes labialis

,

breast implants

,

,

intraocular pressure

,

muscle strength

,

clostridium botulinum type a

healthy volunteers/patients

,

renal insufficiency

,

chronic kidney failure

,

myeloid leukemia acute

,

,

myelodysplastic syndromes

,

non-hodgkin lymphoma

,

,

acquired immunodeficiency syndrome

,

immunologic deficiency syndromes

,

psoriatic arthritis

,

myeloid leukemia

,

,

,

respiratory syncytial virus infections

,

precursor cell lymphoblastic leukemia-lymphoma

,

respiratory syncytial viruses

,

,

venous thrombosis

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

smoldering multiple myeloma

,

,

neoplasm metastasis

,

,

,

chronic hepatitis c

,

,

,

breast neoplasms

,

,

peripheral nervous system diseases

,

hematologic neoplasms

,

colorectal neoplasms

,

,

graft vs host disease

,

bronchiolitis obliterans syndrome

,

multiple myeloma

,

plasma cell neoplasms

,

,

non-small-cell lung carcinoma

,

,

,

,

communicable diseases

,

,

,

,

,

lymphoid leukemia

,

,

depressive disorder

,

ovarian neoplasms

,

,

juvenile arthritis

,

,

respiratory tract infections

,

,

major depressive disorder

,

treatment-resistant depressive disorder

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

ovarian epithelial carcinoma

,

b-cell chronic lymphocytic leukemia

,

respiratory insufficiency

,

rheumatic diseases

,

collagen diseases

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

,

,

psychotic disorders

,

bipolar disorder

,

psychotic affective disorders

,

,

mental disorders

,

venous thromboembolism

,

thromboembolism

,

,

type 2 diabetes mellitus

,

,

diabetes mellitus

,

prostatic neoplasms

,

urogenital neoplasms

,

male genital diseases

,

male genital neoplasms

,

genital diseases

,

,

,

attention deficit disorder with hyperactivity

,

cognitive dysfunction

,

thyroid neoplasms

,

papillary thyroid cancer

,

thyroid diseases

,

,

,

retinal diseases

,

,

ankle fractures

,

,

joint dislocations

,

fibula fractures

squamous cell carcinoma of head and neck

,

primary myelofibrosis

,

healthy volunteers/patients

,

uterine cervical neoplasms

,

cholangiocarcinoma

,

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

colorectal neoplasms

,

,

,

stomach neoplasms

,

b-cell lymphoma

,

triple negative breast neoplasms

,

large b-cell lymphoma diffuse

,

,

ovarian neoplasms

,

,

hepatocellular carcinoma

,

liver neoplasms

,

,

,

non-hodgkin lymphoma

,

ulcerative colitis

,

,

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

small cell lung carcinoma

,

ovarian epithelial carcinoma

,

neoplasm metastasis

,

,

,

,

,

peritoneal neoplasms

,

lupus nephritis

,

,

,

ductal carcinoma breast

,

macular degeneration

,

urinary bladder neoplasms

,

renal cell carcinoma

,

fallopian tube neoplasms

,

,

head and neck neoplasms

,

,

mucinous adenocarcinoma

,

inflammatory breast neoplasms

,

paroxysmal hemoglobinuria

,

,

pancreatic neoplasms

,

,

squamous cell carcinoma

,

urologic neoplasms

,

prostatic neoplasms

,

transitional cell carcinoma

,

colonic neoplasms

,

multiple sclerosis

,

,

,

,

wet macular degeneration

,

follicular lymphoma

,

systemic scleroderma

,

diffuse scleroderma

,

retinal vein occlusion

,

,

,

hemolytic-uremic syndrome

,

atypical hemolytic uremic syndrome

,

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

autistic disorder

,

autism spectrum disorder

,

pervasive child development disorders

,

geographic atrophy

,

,

systemic lupus erythematosus

,

nephrotic syndrome

,

,

lipoid nephrosis

,

esophageal squamous cell carcinoma

,

esophageal neoplasms

,

castration-resistant prostatic neoplasms

,

retinal diseases

,

diabetic retinopathy

,

thyroid neoplasms

,

neuroendocrine carcinoma

,

papillary thyroid cancer

,

thyroid diseases

,

disease progression

,

endometrioid carcinoma

,

,

giant cell arteritis

,

polymyalgia rheumatica

,

type 2 diabetes mellitus

,

diabetes mellitus

,

kidney diseases

,

membranous glomerulonephritis

,

chronic progressive multiple sclerosis

,

,

ankylosing spondylitis

,

spondylarthritis

,

,

residual neoplasm

,

myeloid leukemia acute

,

myeloid leukemia

,

alzheimer disease

,

coronary disease

,

acute coronary syndrome

,

coronary artery disease

,

myocardial ischemia

,

,

relapsing-remitting multiple sclerosis

,

guillain-barre syndrome

,

autoimmune diseases of the nervous system

,

hashimoto disease

,

,

partial epilepsies

,

bcr-abl positive chronic myelogenous leukemia

,

disability evaluation

,

cognition disorders

,

cytomegalovirus infections

,

,

hemolytic anemia autoimmune

,

hemolytic anemia

,

mantle-cell lymphoma

,

,

neoplasms by site

,

breast diseases

,

endometrial neoplasms

,

,

graft rejection

,

choroidal neovascularization

,

,

retinal neovascularization

,

pathologic neovascularization

,

human influenza

,

breast neoplasms

,

non-small-cell lung carcinoma

,

,

,

adenocarcinoma of lung

,

,

postmenopausal osteoporosis

,

carotid stenosis

,

ischemic stroke

,

,

pathologic constriction

,

,

,

myocardial infarction

,

,

,

,

cardiogenic shock

,

coronary artery disease

healthy volunteers/patients

,

,

uterine hemorrhage

,

myocardial infarction

,

st elevation myocardial infarction

,

dual anti-platelet therapy

,

,

coronary artery disease

,

renal insufficiency

,

ischemic stroke

,

,

coronary disease

,

myocardial ischemia

,

hematologic diseases

,

,

blood coagulation disorders

,

hemorrhagic stroke

,

thrombocytopenia

,

hemostatic disorders

,

coagulation protein disorders

,

,

cardiovascular diseases

,

unstable angina

,

st elevation myocardial infarction

,

pharmacological phenomena

,

coronary artery disease

,

myocardial ischemia

,

coronary disease

,

acute coronary syndrome

,

,

myocardial infarction

,

,

percutaneous coronary intervention

,

drug-eluting stents

,

atherosclerosis

,

atrial fibrillation

,

vascular diseases

,

coronary stenosis

,

coronary restenosis

,

,

coronary thrombosis

,

type 2 diabetes mellitus

,

,

healthy volunteers/patients

,

,

,

platelet aggregation

,

,

peripheral arterial disease

,

peripheral vascular diseases

,

,

drug resistance

,

migraine disorders

,

patent foramen ovale

,

dual anti-platelet therapy

,

,

acute kidney injury

,

,

acute liver failure

,

,

postoperative hemorrhage

,

surgical blood loss

,

,

bariatric surgery

,

gastrointestinal hemorrhage

,

peptic ulcer hemorrhage

,

intracranial arteriosclerosis

,

arteriosclerosis

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